From the news that the Ministry of Public Health issued a warning about “Tramadol”   or the green-yellow medicine. It’s a dangerous drug. This makes many people wonder what Tramadol is, what it is used to treat, according to the Mahidol University website. Faculty of Medicine Sirirat Hospital Has come out to provide information about the drug that

Tramadol (Tramadol) is a painkiller. Opioids are used to treat acute and chronic moderate to severe pain, such as pain from wounds, broken bones, and nerve injuries. It should not be used for minor pain.  

There are 2 mechanisms of action:

Stimulating the mu-receptor (µ-receptor) has the effect of reducing pain. and has the effect of depressing the work of the central nervous system Causes a state of bliss (euphoria).  
2. Inhibits the reuptake of the monoamine neurotransmitter (monoamine), which is norepinephrine. (norepinephrine) and serotonin (serotonin) increases the amount of these two substances and reduces pain.

Recommended dose

The starting dose for adults is 50 milligrams at a time every 4-6 hours during pain. The
maximum dose for adults should not exceed 400 milligrams per day.

Tramadol overdose Nowadays, it is very common among teenagers who misuse drugs for relaxation and if used for a long time. There will be addiction. and causes adverse reactions, including mood swings, dizziness, drowsiness,สมัคร ufabet, and lethargy.

Symptoms of overdose include drowsiness, loss of consciousness, nausea and vomiting, dizziness, and rapid heartbeat. Low/high blood pressure, seizures, deep unconsciousness,
so taking Tramadol overdose. and the use of drugs for the wrong purpose. It can cause life-threatening adverse events.

If you want to consult about drugs and toxicology You can call for advice at the Drug and Toxicology Information Unit, call 0-2419-7007.

References
Chulathida Chomchai. Tramadol. In: Sammon Chomchai, Chulathida Chomchai, editor. Poisoning from recreational drugs in teenagers. Bangkok: Siriraj Publishing House; 2017. Pages 141-9.

Check information: Pharmacy Department Siriraj Hospital
Design: Media Production and Services Medical Education Technology Institute
content creator : Health promotion work Faculty of Medicine Siriraj Hospital